Diazepam is used to treat anxiety, alcohol withdrawal, and seizures. It is also used to relieve muscle spasms and to provide sedation before medical procedures. This medication works by calming the brain and nerves. Diazepam Valium 10mg belongs to a class of drugs known as benzodiazepines.
Valium (diazepam) is a benzodiazepine derivative. The chemical name of diazepam is 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin- 2-one. It is a colorless to light yellow crystalline compound, insoluble in water. The empirical formula is C16H13ClN2O and the molecular weight is 284.75.
this product is available for oral administration as tablets containing 2 mg, 5 mg or 10 mg diazepam. In addition to the active ingredient diazepam, each tablet contains the following inactive ingredients: anhydrous lactose, corn starch, pregelatinized starch and calcium stearate with the following dyes: 5-mg tablets contain FD&C Yellow No. 6 and D&C Yellow No. 10; 10-mg tablets contain FD&C Blue No. 1. Valium 2-mg tablets contain no dye.
Uses for Diazepam Valium 10mg
Valium is indicated for the management of anxiety disorders or for the shortterm relief of the symptoms of anxiety. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic.
In acute alcohol withdrawal, Valium may be useful in the symptomatic relief of acute agitation, tremor, impending or acute delirium tremens and hallucinosis.
Valium is a useful adjunct for the relief of skeletal muscle spasm due to reflex spasm to local pathology (such as inflammation of the muscles or joints, or secondary to trauma), spasticity caused by upper motor neuron disorders (such as cerebral palsy and paraplegia), athetosis, and stiff-man syndrome.
Oral Valium may be used adjunctively in convulsive disorders, although it has not proved useful as the sole therapy.
The effectiveness of Valium in long-term use, that is, more than 4 months, has not been assessed by systematic clinical studies. The physician should periodically reassess the usefulness of the drug for the individual patient.
Dosage for Diazepam Valium 10mg
Dosage should be individualized for maximum beneficial effect. While the usual daily dosages given below will meet the needs of most patients, there will be some who may require higher doses. In such cases dosage should be increased cautiously to avoid adverse effects.
ADULTS: | USUAL DAILY DOSE: |
Management of Anxiety Disorders and Relief of Symptoms of Anxiety. | Depending upon severity of symptoms – 2 mg to 10 mg, 2 to 4 times daily |
Symptomatic Relief in Acute Alcohol Withdrawal. | 10 mg, 3 or 4 times during the first 24 hours, reducing to 5 mg, 3 or 4 times daily as needed. |
Adjunctively for Relief of Skeletal Muscle Spasm. | mg2 to 10 mg, 3 or 4 times daily |
Adjunctively in Convulsive Disorders. | 2 mg to 10 mg, 2 to 4 times daily |
Geriatric Patients, or in the presence of debilitating disease. | 2 mg to 2.5 mg, 1 or 2 times daily initially; increase gradually as needed and tolerated. |
PEDIA TRIC PATIENTS: | |
Because of varied responses to CNS-acting drugs, initiate therapy with lowest dose and increase as required. Not for use in pediatric patients under 6 months. | 1 mg to 2.5 mg, 3 or 4 times daily initially; increase gradually as needed and tolerated. |
Discontinuation Or Dosage Reduction Of Valium
To reduce the risk of withdrawal reactions, use a gradual taper to discontinue Valium or reduce the dosage. Furthermore If a patient develops withdrawal reactions, consider pausing the taper or increasing the dosage to the previous tapered dosage level. Subsequently decrease the dosage more slowly (see WARNINGS: Dependence and Withdrawal Reactions and Drug Abuse And Dependence: Dependence).
HOW SUPPLIED
For oral administration, Valium is supplied as round, flat-faced scored tablets with V-shaped perforation and beveled edges. Valium is available as follows:
2 mg, white – bottles of 100 (NDC-80725-004-01)
5 mg, yellow – bottles of 100 (NDC-80725-005-01)
10 mg, blue – bottles of 100 ( NDC-80725-006-01)
Engraved On Tablets
2 mg – 2 and VALIUM® on the outside edge; vertically scored on reverse side
5 mg – 5 and VALIUM® on the outside edge; vertically scored on reverse side
10 mg – 10 and VALIUM® on the outside edge; vertically scored on reverse side
Storage
Store at room temperature 59° to 86°F (15° to 30°C). Dispense in tight, lightresistant containers as defined in USP/NF.
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