Description
Hydrocodone 500mg and acetaminophen combination is used to relieve pain severe enough to require opioid treatment and when other pain medicines did not work well enough or cannot be tolerated.
It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses.
Hydrocodone 500mg medicine belongs to the group of medicines called opioid analgesics (pain medicines). It acts on the central nervous system (CNS) to relieve pain, and stops or prevents cough.
When Hydrocodone 500mg is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using opioids to relieve their pain. Mental dependence (addiction) is less likely to occur when opioids are used for this purpose. Physical dependence may lead to withdrawal symptoms if treatment is stopped suddenly. However, severe withdrawal symptoms can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.
This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Risk Evaluation and Mitigation Strategy) program.
This product is available in the following dosage forms:
- Solution
- Tablet
- Elixir
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. Large amounts of acetaminophen may cause liver damage.
It is very important that you understand the rules of the Opioid Analgesic REMS program to prevent addiction, abuse, and misuse of Hydrocodone 500mg and acetaminophen combination. This medicine should also come with a Medication Guide and patient information leaflet. Read and follow these instructions carefully. Read it again each time you refill your prescription in case there is new information. Ask your doctor if you have any questions.
Measure the oral liquid with a marked measuring spoon, oral syringe, dropper, or medicine cup. The average household teaspoon may not hold the right amount of liquid.
Carefully check the labels of all other medicines you are using, because they may also contain acetaminophen. It is not safe to use more than 4 grams (4,000 milligrams) of acetaminophen in one day (24 hours), as this may increase the risk for serious liver problems. For patients who have a liver condition, the daily maximum limit for acetaminophen use may be lower than 4 grams. Talk to your doctor if you have questions about this.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the Hydrocodone 500mg depend on the medical problem for which you are using the medicine.
- For moderate to severe pain:
- For oral dosage form (10 milligrams [mg] per 325 mg per 15 mL solution):
- Adults—15 milliliters (mL) or 1 tablespoonful every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 90 mL (6 tablespoonfuls) per day.
- Children 14 years of age and older and weighing 46 kg and more—11.25 mL (2 ¼ teaspoonfuls) every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 67.5 mL (13 ½ teaspoonfuls) per day.
- Children 10 to 13 years of age and weighing 32 kg to 45 kg—7.5 mL (1 ½ teaspoonfuls) every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 45 mL (9 teaspoonfuls) per day.
- Children 7 to 9 years of age and weighing 23 kg to 31 kg—5.6 mL (1 teaspoonful) every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 33.6 mL (6 ½ teaspoonfuls) per day.
- Children 4 to 6 years of age and weighing 16 kg to 22 kg—3.75 mL (¾ teaspoonful) every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 22.5 mL (4 ½ teaspoonfuls) per day.
- Children 2 to 3 years of age and weighing 12 kg to 15 kg—2.8 mL (½ teaspoonful) every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 16.8 mL (3 ¼ teaspoonfuls) per day.
- For oral dosage form (tablets):
- Adults—
- Norco® 5/325 (5 milligrams [mg] per 325 mg tablets): 1 or 2 tablets every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 8 tablets per day.
- Norco® 7.5/325 (7.5 mg per 325 mg tablets): 1 tablet every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 6 tablets per day.
- Norco® 10/325 (10 mg per 300 mg tablets): 1 tablet every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 6 tablets per day.
- Adults—1 tablet every 4 to 6 hours as needed. Your doctor may adjust your dose as needed. However, the dose is usually not more than 6 tablets per day.For oral dosage form (10 mg per 300 mg tablets)
- Adults—
- For oral dosage form (10 milligrams [mg] per 325 mg per 15 mL solution):
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